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TD-0903 has potential to inhibit cytokine storm associated with ALI and prevent progression to Acute Respiratory Distress Syndrome
April 23, 2020
By: Kristin Brooks
Managing Editor, Contract Pharma
Theravance Biopharma, Inc. has initiated a Phase I study of TD-0903, a lung-selective, nebulized Janus kinase inhibitor (JAKi) in development for the potential treatment of hospitalized patients with Acute Lung Injury (ALI) caused by COVID-19. TD-0903 has the potential to inhibit the cytokine storm associated with ALI and prevent progression to Acute Respiratory Distress Syndrome (ARDS). The study will assess the safety, tolerability and pharmacokinetics of single- and multiple-ascending dose...
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